William's Fund

Latest Research Update from Chris Mitchell at John Radcliffe Hospital - April 2010

We are looking nanoparticles as a means of delivering small molecules selectively to cancer cells. The initial work is being carried out by a "sandwich" student as there is some initial work to demonstrate the proof of principle.

Elizabeth Rapa, in her PhD and immediate post-doctoral work, demonstrated that it was possible to inhibit the spread of rhabdomyosaroma cells in a laboratory test system by using a small RNA molecule. The nanoparticle system might be a good way to deliver the inhibitory molecule selectively to the cancer cells in a patient, so that it had no effect on the normal functions of non-cancerous cells.

We have just finish writing up Elizabeth's work and will very shortly be submitting it for publication. Elizabeth was awarded her PhD in September 2008, and was in part supported by William's fund.

Over the next year we hope to develop the nanoparticle system further and fund a PhD student to work on it for a three year period. We hope that the student will be the "William Dodd Fellow", and that person will be very largely funded by William's Fund.

Stoke Park Golf Invitational

Liz David the other wonderful organizer!	Guests and players	Guests and players
Guests and players	Guests and players	Guests and players
Dominic Hampshire the wonderful organizer!	Ben Simpson winner of most golf awards and donator of lots of auction prizes!	Emma Hargreaves wins Lady player award.
John McGuinness England Bowls player held a magnificent auction with panache!

Would like to say a big thank you and congratulations to Kevin who ran 2 back to back marathons to raise funds for Williams Fund, one of which was the London Marathon which Kevin finished in 3hrs 40 mins, he has a Just Giving page at: http://www.justgiving.com/kevin-McGilvray Well done Kevin!!

Angels Gather Here 6 Nov 2009 Cozy Christmas Fair……Wow what can I say? Another cozy year at Chris’s cozy house! Familiar faces dropping by for a little shopping, soup and friendly chat… what could be better? If you have never been to this event …. You have missed a treat….watch this space for next year!! The raffle, entrance and refreshments were all donated to William’s Fund and this raised an amazing £564 ….wonderful, thanks to Chris and Dawn for another wonderful day.

Christmas Fair - 4 November 2009 - A wonderful sunny day (thanks Wills!) greeted our traders and supporters at the Christmas Fair. The Crazy Catch outdoor pagoda was a wonderful attraction with demonstrations on the equipment by boys (kindly donated by Thorpe House School!), the Crazy Catch certainly went down well and reminds us that we can all have fun outside with the children while getting exercise and practicing ball skills…a real winner for families and clubs. If you missed it you can follow the link to Flicx and if you decide to buy anything please say you came through William’s Fund and we will get our 10%! Thank you.

Once past the door we were greeted by Kristina Streatfield and her wonderful table designs… you can have all your entertaining tables designed and laid out for those special occasions…they look magnificent and really set the scene!

Up the stairs led to plants donated by Snush Designs, Cakes (mostly baked by Jo Ollis and Heather..thank you ladies), William’s Fund Christmas Cards and the amazing Robin demonstrating the very new SPRAYZ pens… almost blow pens but with a difference…and a little magic thrown in! Once again Robin was selling this new product only found in Hamleys but at a much better price…just for us!! Hope the children all enjoy them! I know mine will.

In the kitchen were the magnificent team of Liz, Barbara and Jill serving a delicious selection of their homemade soup, chili (thanks Jane too!)and cakes to keep everyone well fed and watered while they shopped! Thank you ladies!

Onto more shopping… MMMMmmm Liz David Chocs, Fine Oil and Spice… Tim just has to be there to keep us amused, and where else could we get such fantastic oils and balsamic?! (and insults) then on to Clare Simcock glassware, The ilk Corporation with the lovely Lisa and those extremely talented Cool Chicks! Jewels and decoration from Bali, Treasures and Treats, Fingerprint jewellery from Sue and Christmas decs from the Tythe Barn. Our wonderful Beadazzle with their ever changing goodies to tempt us and of course Will from Millennium Trees …an annual necessity and SUCH a great service ! Downstairs we had Book events with their value books which just walked out… and our wonderful new find… Bailey Park with a stunning array of gifts for everyone. I managed to get most of my Christmas shopping on this one day! To end the day we drew the Jo Ollis Dining Extravaganza draw which was very popular … winners were Sam Thompson, Yvonne Mullally and Sally Lomax…congratulations girls…enjoy!

Thank you to everyone who came along to add to the lovely atmosphere and support us, all the raffle prizes are allocated and delivered and so now we just need to get working on next year…. Which is going to be REVAMPED, va va voomed and very exciting….so watch this space!

Total raised…. Christmas Fair £2541 Dining Extravaganza Draw £3333 … an amazing result…. Thank you to our helpers, we couldn’t do it without you!

Johanna was on Radio Oxford 3 Nov 2009 - promoting William's Fund and the Christmas cards.

Well Alyson I am off to bed but I must send you all sorts of exciting info for special fund raising ideas…I just have to collate the info and arrange it…. Very exciting stuff!

Chrysalis Community Choir sang on Sunday 8 November at 7pm at Chesham Park Community College, Chesham - An evening to remember - a charity concert in aid of Brain Tumour UK and William's Fund.

Johanna live on Radio Oxford 17 March 2009 -listen to the broadcast (these are large files to download: 3MB for part 1 and 5MB for part 2. Please note they are in .mp3 format)

Livi and Ella ran the London Santa run for us and raised £100 (see right)

The Beehive and Honeycomb Nursery in Fulmer once again supported us with proceeds from their Christmas Concert…another £150, thank you so much.

Jordan’s Junior Strings performed beautifully at the Eden Centre in High Wycombe in December. Crowds were amazed at how well all the very young children played…without any sheet music!! Well done everyone and congratulations on raising £300.18, you were brilliant!

Jordans School sent £66 as a donation from their charity event – Thank you!

St Mary’s School Gerrards Cross sent £66.37 from their Young Enterprise Scheme profits, Thank you girls and well done.

The William's Fund Christmas Fair raised £2,819.16 - another fantastic day!

The Angels Gather Here Cozy Christmas Fair raised £366.13 on a splendid chilly day.

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